Developmental toxicity of four glycol ethers applied cutaneously to rats.
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منابع مشابه
Developmental toxicity of four glycol ethers applied cutaneously to rats.
Previous NIOSH studies demonstrated the embryo- and fetotoxicity and teratogenicity of ethylene glycol monoethyl ether (EGEE) applied to the shaved skin of pregnant rats. In the present study ethylene glycol monoethyl ether acetate (EGEEA), ethylene glycol monobutyl ether (EGBE), and diethylene glycol monoethyl ether (diEGEE) were tested in the same experimental model, using distilled water as ...
متن کاملErratum to "Developmental toxicity studies of four fragrances in rats".
The Publisher wishes to appologise that the dosages of HHCB and AHTN were listed incorrectly in the above article. Page 173, left column, lines 11 to 21 should correctly read: Based on estimated maximal daily dermal dosages of 0.11 mg/kg/day of HHCB and 0.043 mg/kg/day of AHTN and 0.025 mg/kg/day of musk ketone and 0.014 mg/kg/day of musk xylene in humans (unpublished industry survey), the mate...
متن کاملDevelopmental toxicity and structure/activity correlates of glycols and glycol ethers.
In recent years, the National Toxicology Program (NTP) has selected numerous glycol ethers for testing in routine laboratory mammals to ascertain the magnitude of their ability to injure the conceptus. From the lists available of ongoing and projected NTP test chemicals, a series of glycol ethers was selected for examination in vitro in the hydra assay. Also tested were additional chemicals of ...
متن کاملDevelopmental toxicity studies of four fragrances in rats.
Four fragrances, 6-acetyl-1,1,2,4,4,7-hexamethyltetraline (AHTN), 1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylcyclopenta-gamma-2-ben zopyran (HHCB), musk ketone and musk xylene were tested for developmental toxicity in Sprague-Dawley rats (25/group, 3 groups/fragrance, 2 fragrances/corn oil control). Dosages tested were HHCB: 50, 150, 500 mg/kg per day; AHTN: 5, 15, 50 mg/kg per day; musk keton...
متن کاملMeasuring exposures to glycol ethers.
In 1981, NIOSH began investigating the potential reproductive health effects resulting from exposures to a class of organic solvents known generically as glycol ethers (GE). This research was begun as a result of the NIOSH criteria document development program which revealed little data available on the health effects of glycol ether exposure. Toxicologic research was begun by NIOSH and other r...
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ژورنال
عنوان ژورنال: Environmental Health Perspectives
سال: 1984
ISSN: 0091-6765,1552-9924
DOI: 10.1289/ehp.845769